The Ohio Department of Transportation reported I-90 westbound was closed from SR-2 just before noon.
The road reopened a few hours later around 2 p.m.
Video from SkyFox showed an overturned semi.
Towing crews were on the scene. Motorists are being asked to avoid the area.
There are no reports of injuries.
FOX 8 is working to learn more about the accident. Stay with us on-air and online for the latest.