According to a press release, the ambulance had its lights and sirens activated and was headed northbound on State Route 252.
The ambulance went through a red light at State Route 82 in Columbia Township when it was hit by a car going westbound.
The impact of the crash caused the ambulance to flip over.
The ambulance was transporting a patient at the time.
OSHP says people in both vehicles were treated for minor injuries.