Chief Calvin Williams said the shooting happened around 2:45 a.m. and that police are now looking for Raymond Melton, wanted for aggravated murder.
Melton has been known to drive two different SUVs, with license plate numbers JYX3536 and JVJ7225.
The suspect is considered armed and dangerous and police said anyone who sees him should call 911.
The victims’ identities have not yet been released.
No motive has been given for the shooting. Richmond Heights detectives are currently investigating and more information is expected to be released at a later time.