Sam is only five years old, but he’s already battled through a lot in those few years.
He suffers from “bubble boy” disease and has to live in a completely sterile environment.
In the video above, he talks about loving Fireman Sam, Paw Patrol and the color yellow.
Although he was born without an immune system, the young boy still has a huge smile on his face, despite needing another bone marrow transplant.
His surgery is on March 27 and he is asking for everyone to wear yellow to help support him. He wants people to post to Facebook, Twitter and Insagram with #wearyellowforSeth and his parents will share the photos with him.