Orkin ranked the cities according to who had the most calls for exterminators to get rid of bed bugs.
Cleveland/Akron/Canton came in at number six, up two places from last year.
Chicago is number one.
Los Angeles is in second place, followed by Columbus, Detroit, and Cincinnati.
"Well, it's not a surprise that we still have a bed bug problem in Cleveland and the surrounding suburbs," Joe Lynch with the Cuyahoga County Board of Health and part of the Cuyahoga County Bed Bug Task Force - yes, the problem is that bad; it has a task force.
They even hold a bed bug conference each year.
The problem with bed bugs, versus other bugs, is bed bugs are so hard to get rid of.
Getting rid of bed bugs can cost hundreds to thousands of dollars and experts say over-the-counter- products don't work.
A clean house does make the bugs easier to spot. But bed bugs are prolific hitchhikers and can be picked up anywhere.
In January, some were found in a courtroom at the Justice Center.
In 2012, there were some at the federal building on East Ninth.
Those bugs were reportedly all exterminated.
"If people do see a bed bug in their house or apartment, please call a professional. The sooner you take care of the problem the less costly it's going to be," Lynch said.
The list, released by Orkin, ranks the cities by the number of bed bug treatments Orkin performed from January to December 2013, along with any shift in ranking compared to January to December 2012.