President: IRS Actions ‘Inexcusable’; Commissioner Resigns

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(CNN) -- President Barack Obama said Wednesday that the "misconduct" detailed in a report about the Internal Revenue Service's handling of requests from conservative groups is "inexcusable." "Americans have a right to be angry about it, and I am angry about it," he said.

Treasury Secretary Jack Lew requested -- and has accepted -- the resignation of the acting commissioner of the Internal Revenue Service in the wake of its handling of requests by conservative groups for tax-exempt status, President Barack Obama also said.

The president said his administration is working to enact "new safeguards to make sure that this kind of behavior cannot happen again."

In a letter to Internal Revenue Service employees, acting IRS Commissioner Steven Miller announced "with regret" that he'll be leaving the agency in early June. "This has been an incredibly difficult time for the IRS given the events of the past few days, and there is a strong and immediate need to restore public trust in the nation's tax agency," said Miller, a 25-year IRS veteran. "I believe the Service will benefit from having a new acting commissioner in place during this challenging period."

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