Funniest Tweets on 2nd Presidential Debate

(CNN) — Every debate seems destined to have a break-out meme. In the first round, it was Big Bird. This time it was Mitt Romney’s binder full of women, which instantly became a trending hashtag, Twitter handle, a Facebook group and a Tumblr. (Talking about his effort to hire women for his cabinet, Romney said “And I brought us whole binders full of, of women.”)

Other popular, bipartisan bits of mockery covered the far livelier and sometimes cringe-inducing tone of the debate, shout outs to Mr. Gas, Mr. Coal and Mr. Oil, the candidates difficulty saying the name Lorraine and the audience members themselves.

*Click here to read more about the second presidential debate

Twitter says there were 7.2 million tweets during the 90-minute debate. The most popular moments were an immigration question, Obama’s comment to Romney on China and Romney’s response to a question about raising taxes.

Here are some of our favorite tweets of the night. Share yours in the comments.

Elon James White — I feel like Obama’s staff stabbed him in the chest w/ the adrenaline needle from Pulp Fiction. THAT DUDE IS AWAKE! #twib2012 #debates

adamsorensen — Is there anything more awkward than putting two guys on stools 10 feet apart on a huge stage and asking them to look natural for 90 minutes?

Andy Borowitz — Romney: “Jeremy, if you are illegal, you can get a job working at my house.” #debate

Brian Braiker — i hope the guy with a mustache has a spot in line. and i hope he stands up to say “Mr President, I mustache you a question.”

Dane Cook — Dear everyone in the town hall #debate. Stop reading your questions off your cards like its a hostage note.

Chase Mitchell ‏– We’re about three seconds away from the knife fight from “Beat It.”#debates

dansinker — I FEEL REALLY UNCOMFORTABLE RIGHT NOW.

Samantha Bee — When Obama is talking, Romney makes the same face my Catholic grandmother would make at a Wiccan wedding. #debate

Matt Roller — Before you accuse Romney of not caring about the unemployed, keep in mind he’s been trying to get a new job for a YEAR. #debate

ditzkoff — Mitt Romney read very different Mr. Men books than I did. #mrcoal #mrgas #mroil

pourmecoffee ‏– Romney: I am pro-choice, but only for deporting yourself.

Jordan Zakarin — I agree with Romney that we really don’t need another ‘Fast and the Furious’ sequel. Enough, Vin Diesel. Bipartisan consensus!

Patton Oswalt — “Binders Full of Women” is my favorite Motley Crue album. #debate

Adam Sternbergh — “Binders full of women” is what they find in a serial killer’s apartment.

Steve Agee — Fonzie had binders full of women too. #debate #littleblackbook

Elise Foley — Oh god, I just realized that now people will dress as binders for Halloween.

Bilge Ebiri — Obama: “I passed a law allowing women to get equal pay.” Romney: “I hired women once.” #debate

Josh Tyrangiel — Romney just locked up the Welsh illegal vote.

ThePresObama [Not the real Obama] — Romney is very tough on China. He will only eat off of the most rare and expensive sets available. #debate2012

Clay Johnson — Watching the debates to figure out who to vote for is like watching the World Series to figure out which team to root for.

Dave Weigel — This panel of undecided voters from Daily Kos threads is asking some good questions.

Pat Healy ‏– Fred Armisen was great tonight as every audience member.#Debate

David Weinberger — Well, there goes the gangbanger vote! Nice job, Mr. President! #debate

Feministing — Guns don’t kill people. Single mothers kill people.

Andy Borowitz — It’s as if the Romney from the first debate is tied up in a Scooby-Doo warehouse somewhere. #debate

Team Coco — You know who won this #debate? The shadowy townhall industry.

Jesse Tyler Ferguson — That debate was better than a real housewives reunion.

– CNN’s Brandon Griggs contributed to this story.